Lipid Species Imaging

Desorption ionization and imaging MS

• this section describes guidelines for various desorption ionization and imaging MS techniques, including.:
  • matrix-assisted laser desorption/ionization, MALDI
  • secondary ion mass spectrometry, SIMS
  • desorption ESI
• lipid species identification is based on principles discussed for shotgun lipidomics
• type of lipid ions generated in the ionization process should be evaluated
• additional evidence from other methods should be used to justify the correct lipid species identification