Quality Control

Each batch should include several analytical controls:

• Blanks to monitor chemical/lipid background and carryover as a sources of artefacts:
  • Solvent blank
  • Internal standard blank
  • Extraction blank
• Quality control samples (QCs) to demonstrate comparable concentrations and coverage of lipid species between different batches within one or between different laboratories
• QCs and reference material should have the same matrix as the sample material
• Reference materials like NIST SRM 1950 are necessary to permit community wide comparability